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Software for motif discovery and next generation sequencing analysis

HOMER (Hypergeometric Optimization of Motif EnRichment) is a suite of tools for Motif Discovery and ChIP-Seq analysis. It is a collection of command line programs for unix-style operating systems written in mostly perl and c++. Homer was primarily written as a de novo motif discovery algorithm that is well suited for finding 8-12 bp motifs in large scale genomics data.

Hardware Requirements (recommended): 2+ Gb memory (4-8+ Gb), 10+ Gb Hard Drive space (50+ Gb)
Software Requirements: Unix compatible OS (or cygwin), perl, gcc, make, wget (optional for full functionality: R, DESeq2, blat, bedGraphToBigWig, liftOver)
License: GPLv3

HOMER works on pretty much any Linux/UNIX systems, including MacOS (if Xcode compilers are installed) and on Windows using either cygwin or a Linux subsystem.

If you are looking specifically for HOMER2, you are in the right place! HOMER2 is integrated into HOMER.

Full Program Download

Search the subreddit. Users frequently share Google Drive or MediaFire links. Look for posts titled: "Does anyone have the KOF Theory Mercenary 400-slot .def?" The community is helpful; just ask politely.

Enjoy the build! Don't forget to like and subscribe for more MUGEN content!

  • Startup time:
  • Optimizations:

    • Rename your current data folder to data_old. The screenpack will overwrite your system files.

    Program Components and Older Versions

    Kof Theory Mercenary Screenpack 400 Slots Down Link -

    Search the subreddit. Users frequently share Google Drive or MediaFire links. Look for posts titled: "Does anyone have the KOF Theory Mercenary 400-slot .def?" The community is helpful; just ask politely.

    Enjoy the build! Don't forget to like and subscribe for more MUGEN content! kof theory mercenary screenpack 400 slots down link

  • Startup time:
  • Optimizations:

    • Rename your current data folder to data_old. The screenpack will overwrite your system files. Search the subreddit


    Update Information

    Change Log - Short description of recent changes

    update.txt - Current HOMER configuration list (Currently support human hg17/hg18/hg19, mouse mm8/mm9, rat rn4, X. tropicalis xenTro2, drosophila dm3, and C. elegans ce6, Zebrafish danRer7, yeast sacCer2, Arabidopsis tair10, Rice msu6, Pombe ASM294v1)
    kof theory mercenary screenpack 400 slots down link
    Can't figure something out? Questions, comments, concerns, or other feedback:
    cbenner@ucsd.edu