Assuming you’ve obtained a reliable portable version:

You can create your own "portable-like" setup by:

But this is not truly portable and often fails due to missing COM registrations.

No. VB6 always generates 32-bit executables. Those run fine on 64-bit Windows via WOW64.

Your compiled .exe will only run on another machine if that PC has the VB6 runtime (MSVBVM60.DLL). Windows 10/11 include it by default (since it’s a system component). For older Windows versions, copy MSVBVM60.DLL from your portable folder into the same directory as your compiled app.