Samtool Supported Models May 2026
The A-series is the most repaired line globally. SAMTool excels here, especially with Exynos chips.
We ran three standard models on a WGS dataset (30x coverage, GRCh38, 100GB BAM) on an AWS c5.4xlarge instance (16 vCPUs, 32GB RAM).
| Model/Command | Time (real) | Peak RAM | Output size (VCF) |
| :--- | :--- | :--- | :--- |
| Model A: samtools view -h in.bam chr1 (extract) | 12s | 1.2GB | 4.5GB (SAM) |
| Model B: samtools sort -@8 (8 threads) | 14m 22s | 6.8GB | 95GB (BAM) |
| Model C: samtools mpileup -uf ref.fa in.bam | bcftools call -mv | 48m 31s | 2.1GB | 2.3MB (VCF) |
| Model D: GATK HaplotypeCaller (for comparison) | 3h 12m | 8.7GB | 3.1MB (VCF) |
Observation: The SAMtools-supported model (C) is 4x faster than GATK for variant calling but yields ~35% more raw variants (mostly due to lower sensitivity to indels). The memory efficiency (2.1GB) makes it suitable for cloud spot instances.
For custom model integration, use samtool.register_model() with your own checkpoint.
SamsTool Online (by the Z3X Team) is a subscription-based diagnostic and repair utility for Samsung smartphones and tablets. It supports a wide range of devices across various chipset architectures, including the latest generations of Exynos, Qualcomm, MediaTek (MTK), and Unisoc based Samsung devices. Supported Chipsets & CPU Models
The tool offers specialized support for several processor families, particularly through EUB (Exynos USB Boot) mode for advanced repairs: Exynos Series: Exynos 3830 (Exynos 850) Exynos 9830 (Exynos 990) Exynos 881 (Exynos 1280) Exynos 8535 (Exynos 1330) Exynos 8835 (Exynos 1380) Exynos 9840 (Exynos 2100) Exynos 1480 (Added in version 1.9 for Galaxy A55 5G models)
MediaTek (MTK): Recent updates added support for the Galaxy A04/A05 series and newer firmware for MTK-based repairs and patching.
Qualcomm: Supports various "BIT" versions and EDL loaders for models like the Galaxy S21 , S20 , and Tab S7 FE . Recently Added Devices (Late 2025)
According to recent updates, the following specific models have been added to the support list: Galaxy A Series: , , , , , Galaxy M/F Series: , , , , , Tablets: (various bits), Core Supported Functions
The tool is designed for professional technicians and provides the following key capabilities across supported models: samtool supported models
Security & Locks: Reset FRP (Google Lock), unlock/relock bootloader, and unlock network or regional locks.
Advanced Repair: Repair IMEI, Repair SN (Serial Number), Patch Certificate, and repair boot for Exynos-based phones.
Maintenance: Switch to EUB mode, change CSC (Country Specific Code), firmware updates, and partition management.
For a complete and live list of supported functions per device model, you can refer to the official Z3X-Team Support Page. SamsTool Online - z3x-team
SamsTool Online software, developed by the , is a professional utility for servicing Samsung mobile devices. It is frequently updated to include the latest hardware generations and specialized modes like EUB (Exynos USB Booting) Supported Hardware Families
The tool supports Samsung devices built on the following chipset architectures:
: Extensive support for the latest generations, including specialized EUB mode functions for deep repair. MediaTek (MTK) : Recent updates, such as version 1.10 , have added specific models like the Galaxy A06 (SM-A065F, SM-A065M)
: Broad support for various Snapdragon-based Samsung smartphones and tablets.
: Compatibility with entry-level and budget-friendly Samsung devices using these processors. Key Functional Capabilities
The software is designed for both service centers and individual professionals, offering a wide range of maintenance and repair functions: Security & FRP The A-series is the most repaired line globally
: Reset FRP (Factory Reset Protection) locks, remove regional locks, and network factory resets. IMEI & Connectivity
: Repair IMEI, repair MAC addresses, and patch/read/write certificates. Bootloader & Firmware
: Unlock or relock bootloaders, update firmware, and change CSC (Country Specific Code) for region switching. Maintenance
: Switch to EUB mode, manage partitions, reset battery status, and perform full read/write backups of device data (NVM/EFS). Usage & Updates
The tool is a professional servicing device that typically requires an active license or activation from . According to community discussions on platforms like
, it is often preferred for its competitive pricing and reliable performance in specialized modes like EUB. step-by-step guide on how to use a specific function, such as FRP removal IMEI repair
There are two primary tools commonly referred to as "SAMtool" or "Samtools." Depending on your field, you are likely looking for one of the following: Bioinformatics: Samtools In genomics,
is a widely used suite of programs for interacting with high-throughput sequencing data. It does not "support models" in a machine-learning sense, but rather supports specific file formats data structures for sequence alignment: Supported Formats SAM (Sequence Alignment/Map) BAM (binary SAM) Core Capabilities : It provides tools for sorting, merging, indexing
, and retrieving alignment reads. It is often used alongside for variant calling (SNPs and indels).
Fisheries Science: SAMtool (Stock Assessment Methods Toolkit) In ecology and fisheries, is an R package used for evaluating stock assessments through closed-loop simulation. It supports a variety of assessment models Assessment Models : Includes Delay-Difference models , Surplus Production models (e.g., ), and integrated Age-Structured models (e.g., SCA - Statistical Catch-at-Age Conditioning Models : It provides operating models to inform data-rich fisheries management. Paper: Understanding the SAM Landscape These are virtually identical to the A-series
The term "SAMtool" serves as a linguistic bridge between two disparate scientific domains: genomic data processing and fisheries management. This paper delineates the supported architectures of both utilities, emphasizing their foundational roles in their respective fields. 1. Genomic Alignment Manipulation (Samtools)
suite remains the industry standard for managing large-scale genomic datasets. Its primary strength lies in its stream-based architecture
, allowing researchers to pipe data between utilities like BCFtools and HTSlib. By supporting the conversion between human-readable SAM and highly compressed BAM/CRAM formats, it enables efficient storage and rapid querying of next-generation sequencing (NGS) data 2. Stock Assessment and Simulation (SAMtool) Conversely, the SAMtool R package focuses on the Management Procedure (MP) framework
. It integrates diverse biological models, ranging from simple catch-based estimators to complex age-structured statistical models . These models are critical for conditioning operating models
that help scientists predict how fish populations respond to different harvesting strategies. Conclusion
These are virtually identical to the A-series. SAMTool support is excellent.
For somatic mutation calling, SAMtools provides samtools mpileup with the -B (disable BAQ) flag for tumor samples to avoid over-filtering, followed by BCFtools with the -c (consensus caller) or somatic-specific priors.
Critical addition: samtools calmd (Calculate MD tags) is used post-alignment to realign reads based on the reference, reducing false positives in homopolymer regions.
Where SAMtool truly shines is its support for compressed models. The base SAM-H requires ~2.6GB of VRAM, which is prohibitive for many users. SAMtool natively supports:
The core of variant calling in SAMtools is the mpileup model. Given a reference genome and aligned reads, it computes:
Mathematically, the likelihood of a genotype $G$ given read data $D$ is approximated as: $$P(D|G) \propto \prod_reads P(read|G, \textbase qual, \textmap qual)$$
SAMtools implements this using a simple, fast forward-backward algorithm, unlike the pair-HMM used in GATK.