To evaluate the role of Lakshadi Avachoornana in the management of Dushta Vrana with special reference to Diabetic Ulcer: A Case Study

Gratis: Tabela Brasindice Download

Gratis: Tabela Brasindice Download

Case Study

Results

Discussion

Conclusion

Reference

Case Report

Diabetic Ulcer

Swathi C Nair; K M Sweta

2020

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Nair S et al: Lakshadi Avachoornana in management of Dushta Vrana Diabetic Ulcer

It is a case study of a 42-year male patient who presented with the chief complains of ulcer over big toe of right leg since 2 months (K/C/O DM for last 8 years and under medication). He was being treated with oral medications and dressings. Study was done after obtaining an informed consent from the patient. He was treated with the Lakshadi Choorna for dressing daily and Triphala Guggulu 2 BD before food, Amritadi Vati 2 BD after food as internal medication.

Intervention: Lakshadi Choorna was prepared with all aseptic measures, as per the classical reference of Choorna Kalpana. After proper cleaning the drugs, it made into small pieces by chopping. Using pulveriser it was made into fine powder with mesh size of 80 to 120 range. Packing done under aseptic precaution and sterilization done under UV for 20 minutes.

With all aseptic measures ulcer was cleaned with normal saline and Avachoornana was done uniformly over ulcer site. Dressing was done with sterile gauze and pad. Avachoornana was done with the Lakshadi Choorna once daily and observations were done on 7^th, 14^th, 21^st and 40^th day of the treatment.

Figure 1: The method of Lakshadi Choorna preparation.

Raw drugs for Lakshadi Avachoornana

Final product

Figure 2: The method of Lakshadi Avachoornana

Journal of Ayurveda and Integrated Medical Sciences 2022;7(9)198

Nair S et al: Lakshadi Avachoornana in management of Dushta Vrana Diabetic Ulcer

0^th Day

Avachoornanam

7^th Day

14^th Day

21^st Day

Journal of Ayurveda and Integrated Medical Sciences 2022;7(9)199

Nair S et al: Lakshadi Avachoornana in management of Dushta Vrana Diabetic Ulcer

40^th Day

Follow-up

Table 2: Subjective symptoms assessed on 0^th, 7^th, 14^th, 21^st, 40^th day.

Pain Assessment	0 No Pain	1-3 Mild pain	4-6 Moderate pain	7-10 Severe pain
0th day		+
7th day		+
14th day	+
21st day	+
40th day	+
Burning Sensation	Grade 0 No burning	Grade 1 Mild burning	Grade 2 Moderate burning	Grade 3 Severe burning
0th day			+
7th day		+
14th day		+
21st day	+
40th day	+

Table 3: Objective symptoms assessed on 0^th, 7^th, 14^th, 21^st, 40^th day.

Item	Assessment	0^th day Score	7^th day Score	14^th day Score	21^st day Score	40^th day Score
1. Size	1 = Length x width <4 sq. cm 2 = Length x width 4--<16 sq. cm 3 = Length x width 16.1--<36 sq. cm 4 = Length x width 36.1--<80 sq. cm 5 = Length x width >80 sq. cm	3	3	3	3	2
2. Depth	1 = non-blanchable erythema on intact skin 2 = Partial thickness skin loss involving epidermis &/or dermis 3 = Full thickness skin loss involving damage or necrosis of subcutaneous tissue; may extend down to but not through underlying fascia; &/or mixed partial & full thickness &/or tissue layers obscured by granulation tissue 4 = Obscured by necrosis 5 = Full thickness skin loss with extensive destruction, tissue necrosis or damage to muscle, bone or supporting structures	3	3	3	3	3
3. Edges	1 = Indistinct, diffuse, none clearly visible 2 = Distinct, outline clearly visible, attached, even with wound base 3 = Well-defined, not attached to wound base 4 = Well-defined, not attached to base, rolled under, thickened 5= Well-defined, fibrotic, scarred or hyperkeratotic	2	2	2	1	1
4.Undermining	1 = None present 2 = Undermining < 2 cm in any area 3 = Undermining 2-4 cm involving < 50% wound margins 4 = Undermining 2-4 cm involving > 50% wound margins 5 = Undermining > 4 cm or Tunnelling in any area	1	1	1	1	1
5.Necrotic Tissue Type	1 = None visible 2 = White/grey non-viable tissue &/or non-adherent yellow slough 3 = Loosely adherent yellow slough 4 = Adherent, soft, black eschar 5 = Firmly adherent, hard, black eschar	3	3	2	2	1
6.Necrotic Tissue Amount	1 = None visible 2 = < 25% of wound bed covered 3 = 25% to 50% of wound covered 4 = > 50% and < 75% of wound covered 5 = 75% to 100% of wound covered	2	2	2	2	1
7.Exudate Type	1 = None 2 = Bloody 3 = Serosanguineous: thin, watery, pale red/pink 4 = Serous: thin, watery, clear 5 = Purulent: thin or thick, opaque, tan/yellow, with or without odour	3	3	1	1	1
8.Exudate Amount	1 = None, dry wound 2 = Scant, wound moist but no observable exudate 3 = Small 4 = Moderate 5 = Large	4	3	2	2	2

Journal of Ayurveda and Integrated Medical Sciences 2022;7(9)200

Nair S et al: Lakshadi Avachoornana in management of Dushta Vrana Diabetic Ulcer

Reduction of Symptoms of ulcer was achieved within 14-21 days of Lakshadi Avachoornana and later complete healing was achieved without any other complications.

Lakshadi Gana with the properties of Tikta Kashaya Rasa, Laghu Rooksha Guna, Ushna Veerya, Katu Vipaka, Kaphapittahara and Arthi Nashanam is indicated in Dushta Vrana, Kushta and Krimi. Acharya Susrutha has included this Gana in Dravya Sangrahaneeya Adyaya and indicated in Dushta Vrana. In the present situation, due to hampered foot habits and physical exertion, life style disorders are more along with its complications. Lakshadi Avachoornana helps in reducing the symptoms of Dushta Vrana, thereby helps in getting desired

result. Tikta Kashya Rasa helps in promoting healing of wound and it has Pittahara property, thereby helps in reducing the burning sensation.

Due to its Usha Veerya, it helps in Vatashamana, thereby reducing the pain. This Gana also possess, Krimighna, Kushtagna property, hence its Vranasodhana and Ropana nature in Dushta Vrana is highlighted.

Further clinical study is needed to evaluate the effectiveness in larger sample.

Significant relief on symptoms of Dushta Vrana including Poothi Pooya, Srava, Athigandha etc was being observed in the course of treatment. There was better healing and sustained symptomatic relief in this patient with the Lakshadi Avachoornana. Due to its easy and convenient mode of application it makes the procedure significant.

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9. Singh J. Laksha (Lac) - LacciferLacca [Internet]. Ayurtimes.com. 2015 [cited 2021 Jul 4]. Available from: https://www.ayurtimes.com/lac-laccifer-lacca-health-benefits-uses-side-effects.[accessed on 2021-7-1]

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Journal of Ayurveda and Integrated Medical Sciences 2022;7(9)202

Manuscript Received	Review Round 1	Review Round 2	Review Round 3	Accepted
2022-08-29	2022-08-31	2022-09-07	2022-09-14	2022-09-21
Conflict of Interest	Funding	Ethical Approval	Plagiarism X-checker	Note
Nil	Nil	Yes	16%

9.Skin Colour Surrounding Wound

1 = Pink or normal for ethnic group 2 = Bright red &/or blanches to touch 3 = White or grey pallor or hypopigmented 4 = Dark red or purple &/or non-blanchable 5 = Black or hyperpigmented

10.Peripheral Tissue Edema

1 = No swelling or edema 2 = non-pitting edema extends < 4 cm around wound 3 = non-pitting edema extends > 4 cm around wound 4 = Pitting edema extends < 4 cm around wound 5 = Crepitus and/or pitting edema extends >4 cm around wound

11.Peripheral Tissue Induration

1 = None present 2 = Induration, < 2 cm around wound 3 = Induration 2-4 cm extending < 50% around wound 4 = Induration 2-4 cm extending > 50% around wound 5 = Induration > 4 cm in any area around wound

12.Granulation Tissue

1 = Skin intact or partial thickness wound 2 = Bright, beefy red; 75% to 100% of wound filled &/or tissue overgrowth 3 = Bright, beefy red; < 75% & > 25% of wound filled 4 = Pink, &/or dull, dusky red &/or fills < 25% of wound 5 = No granulation tissue present

13.Epithelialization

1 = 100% wound covered, surface intact 2 = 75% to <100% wound covered &/or epithelial tissue extends to > 0.5cm into wound bed 3 = 50% to <75% wound covered &/or epithelial tissue extends to <0.5cm into wound bed 4 = 25% to < 50% wound covered 5 = < 25% wounds covered

Total Score