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| Drug Class | Example | Indication | Onset | Key Monitoring | |------------|---------|------------|-------|----------------| | SSRI | Fluoxetine | Canine separation anxiety, compulsive disorders | 4–6 weeks | Appetite changes, lethargy | | TCA | Clomipramine | Canine separation anxiety, feline urine spraying | 3–4 weeks | Sedation, anticholinergic effects | | SARI | Trazodone | Situational anxiety (vet visits, noise phobia) | 1–2 hours | Hypotension, paradoxical excitation | | Gabapentin | Gabapentin | Chronic pain + anxiety, feline hyperesthesia | Hours–days | Ataxia, sedation |

| Disorder | Species | Clinical Signs | Differential Medical Causes | |----------|---------|----------------|-----------------------------| | Separation anxiety | Dog | Destructiveness, vocalization, hypersalivation when left alone | Cognitive dysfunction, pain, hyperthyroidism (cats) | | Compulsive disorder | Dog, cat | Tail chasing, flank sucking, excessive grooming | Neurological lesions, dermatological allergies | | Inter-cat aggression | Cat | Blocking resources, fighting, inappropriate elimination | Feline lower urinary tract disease (FLUTD), osteoarthritis | | Stereotypies | Horse | Crib-biting, weaving, box-walking | Gastric ulcers, high-concentrate diets, confinement | Zooskool Knotty Likes It Allot.rar Checked

The interplay of animal behavior and veterinary science looks different across species. | Drug Class | Example | Indication |

Aggression, anxiety, and compulsive disorders are not moral failings in animals; they are often the result of altered neurochemistry. Serotonin, dopamine, and norepinephrine regulate mood and impulse control in animals just as they do in humans. A dog with low serotonin levels is not "being stubborn"—it is struggling with impulse control. Veterinary science provides the tools to measure (indirectly) and modify these neurochemical imbalances through selective serotonin reuptake inhibitors (SSRIs) and other psychopharmaceuticals. A dog with low serotonin levels is not